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1.
Подробнее
S 68
Smith, Robert E., (1951-)
Systems thinking in medicine and new drug discovery. / Robert E., (1951-) Smith.
Volume one /. - Newcastle upon Tyne : : Cambridge Scholars Publishing,, ©2018. - 1 online resource (xv, 616 pages) : : il. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/1566C3B2-3B9B-4AF6-9A0C-DC078E916B76. - ISBN 9781527523661 (electronic bk.). - ISBN 1527523667 (electronic bk.)
Print version record.
Параллельные издания: Print version: : Smith, Robert E., 1951- Systems thinking in medicine and new drug discovery. Volume one. - Newcastle upon Tyne : Cambridge Scholars Publishing, 2018. - ISBN 1527506096
~РУБ DDC 615.1/9
Рубрики: Drug development.
Pharmaceutical chemistry.
Integrative medicine.
Human biology.
Drug Discovery.
Drug development.
Human biology.
Integrative medicine.
Pharmaceutical chemistry.
MEDICAL / Pharmacology
S 68
Smith, Robert E., (1951-)
Systems thinking in medicine and new drug discovery. / Robert E., (1951-) Smith.
Volume one /. - Newcastle upon Tyne : : Cambridge Scholars Publishing,, ©2018. - 1 online resource (xv, 616 pages) : : il. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/1566C3B2-3B9B-4AF6-9A0C-DC078E916B76. - ISBN 9781527523661 (electronic bk.). - ISBN 1527523667 (electronic bk.)
Print version record.
Параллельные издания: Print version: : Smith, Robert E., 1951- Systems thinking in medicine and new drug discovery. Volume one. - Newcastle upon Tyne : Cambridge Scholars Publishing, 2018. - ISBN 1527506096
Рубрики: Drug development.
Pharmaceutical chemistry.
Integrative medicine.
Human biology.
Drug Discovery.
Drug development.
Human biology.
Integrative medicine.
Pharmaceutical chemistry.
MEDICAL / Pharmacology
2.
Подробнее
S 68
Smith, Robert E., (1951-)
Systems thinking in medicine and new drug discovery. / Robert E., (1951-) Smith.
Volume two /. - Newcastle upon Tyne : : Cambridge Scholars Publishing,, 2018. - 1 online resource (xiv, 333 pages) : : il. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/3F7C0233-5905-4096-B8F7-FE6BF1308759. - ISBN 9781527523777 (electronic bk.). - ISBN 1527523772 (electronic bk.)
Description based on online resource; title from PDF title page (EBSCO, viewed January 8, 2019).
~РУБ DDC 615.1/9
Рубрики: Drug development.
Pharmaceutical chemistry.
Integrative medicine.
Human biology.
Drug development.
Human biology.
Integrative medicine.
Pharmaceutical chemistry.
MEDICAL / Pharmacology
S 68
Smith, Robert E., (1951-)
Systems thinking in medicine and new drug discovery. / Robert E., (1951-) Smith.
Volume two /. - Newcastle upon Tyne : : Cambridge Scholars Publishing,, 2018. - 1 online resource (xiv, 333 pages) : : il. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/3F7C0233-5905-4096-B8F7-FE6BF1308759. - ISBN 9781527523777 (electronic bk.). - ISBN 1527523772 (electronic bk.)
Description based on online resource; title from PDF title page (EBSCO, viewed January 8, 2019).
Рубрики: Drug development.
Pharmaceutical chemistry.
Integrative medicine.
Human biology.
Drug development.
Human biology.
Integrative medicine.
Pharmaceutical chemistry.
MEDICAL / Pharmacology
3.
Подробнее
S 70
Software innovations in clinical drug development and safety / / Partha Chakraborty and Amit Nagal, editors. - Hershey, PA : : Medical Information Science Reference,, ©2016. - 1 online resource. - (Advances in medical technologies and clinical practice book series). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/C5D32047-0885-4E9C-AC73-7B006A7CF3B8. - ISBN 9781466687271 (electronic bk.). - ISBN 1466687274 (electronic bk.). - ISBN 1466687266 (hardcover). - ISBN 9781466687264 (hardcover)
Online resource; title from PDF title page (EBSCO, viewed October 7, 2015).
Параллельные издания: Print version: : Software innovations in clinical drug development and safety. - Hershey, PA : Medical Information Science Reference, [2016]. - ISBN 9781466687264
Содержание:
Overview of clinical trial and pharmacovigilance process and areas of application of computer system / Sowmyanarayan Srinivasan -- Innovative means and mechanisms of utilizing optimal clinical and safety aligned data structures -- Application of metadata repository and master data management in clinical trial and drug safety / Chandrakant Ekkirala -- Semantic integration, text mining, tools and technologies / Chandrakant Ekkirala -- Safety signal detection in the drug development process : safety signal detection in the drug development / Ramin B. Arani, Antoni F.Z. Wisniewski -- Application of SMAC technology / Manu Venugopal -- Architecture of an integrated collaboration portal for clinical trial a case study / Partha Chakraborty -- Architecture of an integrated regulatory information management platform for clinical trials : a case study in regulatory information management system implementation / Ayan Choudhury -- Personal diagnostics using DNA-sequencing / Udayaraja G.K. -- Pharmacogenomics genome wide association clinical studies / Udayaraja G.K. -- Role of epigenetic in cancer genomics / Amit Nagal -- Impact of human exome sequencing on clinical research / Anu Acharya, Shibichakravarthy Kannan, Brajendra Kumar, Jasmine Khurana, Sushma Patil, Geethanjali Tanikella -- Computer system validation in life sciences industry / Arindam Dey -- Agile methodology of development and how to be compliant / Yerramalli Subramaniam.
~РУБ DDC 615.10285
Рубрики: Pharmacy informatics.
Drug development.
Genomics.
Drug Discovery
Software
Clinical Trials as Topic
Pharmacovigilance
Genomics
Pharmacie--Informatique.
Médicaments--Développement.
Logiciels.
Pharmacovigilance.
Génomique.
software.
MEDICAL--Pharmacology.
Drug development.
Pharmacy informatics.
Аннотация: "This book is a comprehensive resource analyzing the integration of software engineering for the purpose of drug discovery, clinical trials, genomics, and drug safety testing"--Provided by publisher.
Доп.точки доступа:
Chakraborty, Partha, (1972-) \editor.\
Nagal, Amit, (1979-) \editor.\
S 70
Software innovations in clinical drug development and safety / / Partha Chakraborty and Amit Nagal, editors. - Hershey, PA : : Medical Information Science Reference,, ©2016. - 1 online resource. - (Advances in medical technologies and clinical practice book series). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/C5D32047-0885-4E9C-AC73-7B006A7CF3B8. - ISBN 9781466687271 (electronic bk.). - ISBN 1466687274 (electronic bk.). - ISBN 1466687266 (hardcover). - ISBN 9781466687264 (hardcover)
Online resource; title from PDF title page (EBSCO, viewed October 7, 2015).
Параллельные издания: Print version: : Software innovations in clinical drug development and safety. - Hershey, PA : Medical Information Science Reference, [2016]. - ISBN 9781466687264
Содержание:
Overview of clinical trial and pharmacovigilance process and areas of application of computer system / Sowmyanarayan Srinivasan -- Innovative means and mechanisms of utilizing optimal clinical and safety aligned data structures -- Application of metadata repository and master data management in clinical trial and drug safety / Chandrakant Ekkirala -- Semantic integration, text mining, tools and technologies / Chandrakant Ekkirala -- Safety signal detection in the drug development process : safety signal detection in the drug development / Ramin B. Arani, Antoni F.Z. Wisniewski -- Application of SMAC technology / Manu Venugopal -- Architecture of an integrated collaboration portal for clinical trial a case study / Partha Chakraborty -- Architecture of an integrated regulatory information management platform for clinical trials : a case study in regulatory information management system implementation / Ayan Choudhury -- Personal diagnostics using DNA-sequencing / Udayaraja G.K. -- Pharmacogenomics genome wide association clinical studies / Udayaraja G.K. -- Role of epigenetic in cancer genomics / Amit Nagal -- Impact of human exome sequencing on clinical research / Anu Acharya, Shibichakravarthy Kannan, Brajendra Kumar, Jasmine Khurana, Sushma Patil, Geethanjali Tanikella -- Computer system validation in life sciences industry / Arindam Dey -- Agile methodology of development and how to be compliant / Yerramalli Subramaniam.
Рубрики: Pharmacy informatics.
Drug development.
Genomics.
Drug Discovery
Software
Clinical Trials as Topic
Pharmacovigilance
Genomics
Pharmacie--Informatique.
Médicaments--Développement.
Logiciels.
Pharmacovigilance.
Génomique.
software.
MEDICAL--Pharmacology.
Drug development.
Pharmacy informatics.
Аннотация: "This book is a comprehensive resource analyzing the integration of software engineering for the purpose of drug discovery, clinical trials, genomics, and drug safety testing"--Provided by publisher.
Доп.точки доступа:
Chakraborty, Partha, (1972-) \editor.\
Nagal, Amit, (1979-) \editor.\
4.
Подробнее
K 46
Kinch, Michael, (1966-).
A prescription for change : : the looming crisis in drug development / / Michael S. Kinch. - Chapel Hill : : The University of North Carolina Press,, 2016. - 1 online resource (xi, 339 pages). - (The Luther H. Hodges Jr. and Luther H. Hodges Sr. series on business, entrepreneurship, and public policy). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/47D5D659-9ED7-4DE6-91A4-7A05D9FC2ECC. - ISBN 1469630648 (electronic bk.). - ISBN 9781469630649 (electronic bk.)
Print version record.
Параллельные издания: Print version: : Kinch, Michael S. Prescription for change. - Chapel Hill : University of North Carolina Press, [2016]. - ISBN 9781469630625
Содержание:
Introduction: How Did We Reach This Point? -- Why Regulate Medicines? -- Trials and Tribulations -- Dreams of Greatness: The Birth of the Pharmaceutical Industry -- Triumph and Tragedy -- Ivory Tower of Power -- The DNA of Biotechnology -- Blockbusters and Bombs: Pressures on the Pharmaceutical Industry -- Sea Monsters, Immunauts, and Death Panels -- Drama on the I-270 Tech Corridor -- Autophagy -- Three Views of a Train Wreck -- Bridging the Valley.
~РУБ DDC 615.1/9
Рубрики: Drug development.
Drugs--Research--Economic aspects.
Pharmaceutical industry.
Drugs--Design.
Drug Design
Drug Industry
Médicaments--Développement.
Médicaments--Recherche--Aspect économique.
Industrie pharmaceutique.
Médicaments--Conception.
MEDICAL--Pharmacology.
BUSINESS & ECONOMICS--Development--Business Development.
Drug development.
Drugs--Research--Economic aspects.
Pharmaceutical industry.
Аннотация: The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes -- and indeed because of them -- our ability to deliver new medicines may be quickly coming to an end. Moving from the beginning of the twentieth century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy. To explain how we have arrived at this pivotal moment, Michael Kinch recounts the history of pharmaceutical and biotechnological advances in the twentieth century. Kinch relates stories of the individuals and organizations that built the modern infrastructure that supports the development of innovative new medicines. He shows that an accelerating cycle of acquisition and downsizing is cannibalizing that infrastructure Kinch demonstrates the dismantling of the pharmaceutical and biotechnological research and development enterprises could also provide opportunities to innovate new models that sustain and expand the introduction of newer and better breakthrough medicines in the years to come. - Publisher.
K 46
Kinch, Michael, (1966-).
A prescription for change : : the looming crisis in drug development / / Michael S. Kinch. - Chapel Hill : : The University of North Carolina Press,, 2016. - 1 online resource (xi, 339 pages). - (The Luther H. Hodges Jr. and Luther H. Hodges Sr. series on business, entrepreneurship, and public policy). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/47D5D659-9ED7-4DE6-91A4-7A05D9FC2ECC. - ISBN 1469630648 (electronic bk.). - ISBN 9781469630649 (electronic bk.)
Print version record.
Параллельные издания: Print version: : Kinch, Michael S. Prescription for change. - Chapel Hill : University of North Carolina Press, [2016]. - ISBN 9781469630625
Содержание:
Introduction: How Did We Reach This Point? -- Why Regulate Medicines? -- Trials and Tribulations -- Dreams of Greatness: The Birth of the Pharmaceutical Industry -- Triumph and Tragedy -- Ivory Tower of Power -- The DNA of Biotechnology -- Blockbusters and Bombs: Pressures on the Pharmaceutical Industry -- Sea Monsters, Immunauts, and Death Panels -- Drama on the I-270 Tech Corridor -- Autophagy -- Three Views of a Train Wreck -- Bridging the Valley.
Рубрики: Drug development.
Drugs--Research--Economic aspects.
Pharmaceutical industry.
Drugs--Design.
Drug Design
Drug Industry
Médicaments--Développement.
Médicaments--Recherche--Aspect économique.
Industrie pharmaceutique.
Médicaments--Conception.
MEDICAL--Pharmacology.
BUSINESS & ECONOMICS--Development--Business Development.
Drug development.
Drugs--Research--Economic aspects.
Pharmaceutical industry.
Аннотация: The introduction of new medicines has dramatically improved the quantity and quality of individual and public health while contributing trillions of dollars to the global economy. In spite of these past successes -- and indeed because of them -- our ability to deliver new medicines may be quickly coming to an end. Moving from the beginning of the twentieth century to the present, A Prescription for Change reveals how changing business strategies combined with scientific hubris have altered the way new medicines are discovered, with dire implications for both health and the economy. To explain how we have arrived at this pivotal moment, Michael Kinch recounts the history of pharmaceutical and biotechnological advances in the twentieth century. Kinch relates stories of the individuals and organizations that built the modern infrastructure that supports the development of innovative new medicines. He shows that an accelerating cycle of acquisition and downsizing is cannibalizing that infrastructure Kinch demonstrates the dismantling of the pharmaceutical and biotechnological research and development enterprises could also provide opportunities to innovate new models that sustain and expand the introduction of newer and better breakthrough medicines in the years to come. - Publisher.
5.
Подробнее
P 56
PHARMACEUTICAL SCIENCES : : breakthroughs in research and practice. - HERSHEY : : MEDICAL INFOR Science IGI,, 2017. - 1 online resource. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/48286713-11AE-4348-A8D2-D75A979AA71E. - ISBN 9781522517634 (electronic bk.). - ISBN 1522517634 (electronic bk.)
Параллельные издания: Print version: :
~РУБ DDC 338.4/76151
Рубрики: Drug development.
Pharmaceutical industry.
BUSINESS & ECONOMICS / Industries / General
P 56
PHARMACEUTICAL SCIENCES : : breakthroughs in research and practice. - HERSHEY : : MEDICAL INFOR Science IGI,, 2017. - 1 online resource. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/48286713-11AE-4348-A8D2-D75A979AA71E. - ISBN 9781522517634 (electronic bk.). - ISBN 1522517634 (electronic bk.)
Параллельные издания: Print version: :
Рубрики: Drug development.
Pharmaceutical industry.
BUSINESS & ECONOMICS / Industries / General
6.
Подробнее
C 73
Computer applications in drug discovery and development / / A. Puratchikody, S. Lakshmana Prabu, and A. Umamaheswari, editors. - 4018/978-1-5225-7326-5. - Hershey, Pennsylvania (701 E. Chocolate Avenue, Hershey, Pennsylvania, 17033, USA) : : IGI Global,, [2019]. - 1 online resource (20 PDFs (xvi, 332 pages)) ( час. мин.), 4018/978-1-5225-7326-5. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/9A13E30E-FB8D-49AC-B3C1-A33FB67FEF15. - ISBN 1522573275. - ISBN 9781522573272 (electronic bk.)
Description based on title screen (IGI Global, viewed 10/31/2018).
Параллельные издания: Print version: :
Содержание:
Chapter 1. Drug discovery: current state and future prospects -- Chapter 2. Chemical structure databases in drug discovery -- Chapter 3. Lead optimization in the drug discovery process -- Chapter 4. QSAR and lead optimization -- Chapter 5. Virtual screening and its applications in drug discovery process -- Chapter 6. Computational investigation of versatile activity of Piperine -- Chapter 7. Target identification of HDAC8 isoform for the treatment of cancer -- Chapter 8. Molecular modelling studies of novel COX-2 inhibitors -- Chapter 9. Construction and analysis of protein-protein interaction network: role in identification of key signaling molecules involved in a disease pathway -- Chapter 10. Quality by design in pharmaceutical formulation -- Chapter 11. The next generation sequencing techniques and application in drug discovery and development -- Chapter 12. Semantic technologies for medical knowledge representation.
~РУБ DDC 615.1/9
Рубрики: Pharmacology--Data processing.
Drug development.
Drugs--Design.
Drug Discovery.
Software.
MEDICAL / Pharmacology
Аннотация: "This book examines how the use of computers for discovering and designing new drugs is becoming a central topic in modern molecular biology and medicinal chemistry. It also identifies promising compounds that might represent future solutions in critical areas of human health"--Provided by publisher.
Доп.точки доступа:
Puratchikody, A., (Ayarivan), (1970-) \editor.\
Prabu, S. Lakshmana, (Sakthivel Lakshmana), (1974-) \editor.\
Umamaheswari, A., (Appavoo), (1981-) \editor.\
IGI Global,
C 73
Computer applications in drug discovery and development / / A. Puratchikody, S. Lakshmana Prabu, and A. Umamaheswari, editors. - 4018/978-1-5225-7326-5. - Hershey, Pennsylvania (701 E. Chocolate Avenue, Hershey, Pennsylvania, 17033, USA) : : IGI Global,, [2019]. - 1 online resource (20 PDFs (xvi, 332 pages)) ( час. мин.), 4018/978-1-5225-7326-5. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/9A13E30E-FB8D-49AC-B3C1-A33FB67FEF15. - ISBN 1522573275. - ISBN 9781522573272 (electronic bk.)
Description based on title screen (IGI Global, viewed 10/31/2018).
Параллельные издания: Print version: :
Содержание:
Chapter 1. Drug discovery: current state and future prospects -- Chapter 2. Chemical structure databases in drug discovery -- Chapter 3. Lead optimization in the drug discovery process -- Chapter 4. QSAR and lead optimization -- Chapter 5. Virtual screening and its applications in drug discovery process -- Chapter 6. Computational investigation of versatile activity of Piperine -- Chapter 7. Target identification of HDAC8 isoform for the treatment of cancer -- Chapter 8. Molecular modelling studies of novel COX-2 inhibitors -- Chapter 9. Construction and analysis of protein-protein interaction network: role in identification of key signaling molecules involved in a disease pathway -- Chapter 10. Quality by design in pharmaceutical formulation -- Chapter 11. The next generation sequencing techniques and application in drug discovery and development -- Chapter 12. Semantic technologies for medical knowledge representation.
Рубрики: Pharmacology--Data processing.
Drug development.
Drugs--Design.
Drug Discovery.
Software.
MEDICAL / Pharmacology
Аннотация: "This book examines how the use of computers for discovering and designing new drugs is becoming a central topic in modern molecular biology and medicinal chemistry. It also identifies promising compounds that might represent future solutions in critical areas of human health"--Provided by publisher.
Доп.точки доступа:
Puratchikody, A., (Ayarivan), (1970-) \editor.\
Prabu, S. Lakshmana, (Sakthivel Lakshmana), (1974-) \editor.\
Umamaheswari, A., (Appavoo), (1981-) \editor.\
IGI Global,
Page 1, Results: 6