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1.
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G 89
Grote, Mathias,.
Membranes to molecular machines : : active matter and the remaking of life / / Mathias Grote. - Chicago : : The University of Chicago Press,, ©2029. - 1 online resource (xvi, 286 pages, 4 pages of plates) : : il, вкл.л. - (Synthesis). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/2BB6E378-0352-41D6-93E4-78509B9CBDB1. - ISBN 9780226625294 (electronic bk.). - ISBN 022662529X (electronic bk.)
Online resource; title from PDF title page (EBSCO, viewed July 3, 2019).
Параллельные издания: Print version: : Grote, Mathias. Membranes to molecular machines. - Chicago : The University of Chicago Press, [2019]. - ISBN 9780226625157
Содержание:
Introduction : the molecular-mechanical vision of life -- Part one : Taking membranes apart, isolating a molecular pump -- What membranes can tell a historian and philosopher of the life sciences -- Active matter -- Part two: Remaking membranes and molecular machines -- Synthesizing cells and molecules : mechanisms as "plug-and-play" -- Biochip fever: life and technology in the 1980s -- Conclusion.
~РУБ DDC 572.8
Рубрики: Molecular biology--Research--History.
Membranes (Biology)--Research--History.
Biotechnology--Research--History.
Membranes (Biology)
Membranes
Biomedical Research--history
Biotechnology
Biologie moléculaire--Recherche--Histoire.
Membranes (Biologie)--Recherche--Histoire.
Membranes (Biologie)
Biotechnologie.
bioengineering.
SCIENCE--Life Sciences--Biology--Molecular Biology.
Biotechnology--Research.
Membranes (Biology)--Research.
Molecular biology--Research.
Аннотация: Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing "proton pump inhibitors" or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciences--from practitioner to historian to philosopher
G 89
Grote, Mathias,.
Membranes to molecular machines : : active matter and the remaking of life / / Mathias Grote. - Chicago : : The University of Chicago Press,, ©2029. - 1 online resource (xvi, 286 pages, 4 pages of plates) : : il, вкл.л. - (Synthesis). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/2BB6E378-0352-41D6-93E4-78509B9CBDB1. - ISBN 9780226625294 (electronic bk.). - ISBN 022662529X (electronic bk.)
Online resource; title from PDF title page (EBSCO, viewed July 3, 2019).
Параллельные издания: Print version: : Grote, Mathias. Membranes to molecular machines. - Chicago : The University of Chicago Press, [2019]. - ISBN 9780226625157
Содержание:
Introduction : the molecular-mechanical vision of life -- Part one : Taking membranes apart, isolating a molecular pump -- What membranes can tell a historian and philosopher of the life sciences -- Active matter -- Part two: Remaking membranes and molecular machines -- Synthesizing cells and molecules : mechanisms as "plug-and-play" -- Biochip fever: life and technology in the 1980s -- Conclusion.
Рубрики: Molecular biology--Research--History.
Membranes (Biology)--Research--History.
Biotechnology--Research--History.
Membranes (Biology)
Membranes
Biomedical Research--history
Biotechnology
Biologie moléculaire--Recherche--Histoire.
Membranes (Biologie)--Recherche--Histoire.
Membranes (Biologie)
Biotechnologie.
bioengineering.
SCIENCE--Life Sciences--Biology--Molecular Biology.
Biotechnology--Research.
Membranes (Biology)--Research.
Molecular biology--Research.
Аннотация: Today's science tells us that our bodies are filled with molecular machinery that orchestrates all sorts of life processes. When we think, microscopic "channels" open and close in our brain cell membranes; when we run, tiny "motors" spin in our muscle cell membranes; and when we see, light operates "molecular switches" in our eyes and nerves. A molecular-mechanical vision of life has become commonplace in both the halls of philosophy and the offices of drug companies, where researchers are developing "proton pump inhibitors" or medicines similar to Prozac. Membranes to Molecular Machines explores just how late twentieth-century science came to think of our cells and bodies this way. This story is told through the lens of membrane research, an unwritten history at the crossroads of molecular biology, biochemistry, physiology, and the neurosciences, that directly feeds into today's synthetic biology as well as nano- and biotechnology. Mathias Grote shows how these sciences not only have made us think differently about life, they have, by reworking what membranes and proteins represent in laboratories, allowed us to manipulate life as "active matter" in new ways. Covering the science of biological membranes in the United States and Europe from the mid-1960s to the 1990s, this book connects that history to contemporary work with optogenetics, a method for stimulating individual neurons using light, and will enlighten and provoke anyone interested in the intersection of chemical research and the life sciences--from practitioner to historian to philosopher
2.
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M 29
Marchand, Marie-Hélène,.
The story of the Pasteur Institute and its contributions to global health / / by Marie-Hélène Marchand. - Newcastle upon Tyne, UK : : Cambridge Scholars Publishing,, ©2018. - 1 online resource (xii, 190 pages) : : il, портр. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/2F3088C7-5A2C-4A8D-935C-2BE8634EF113. - ISBN 9781527525610 (electronic bk.). - ISBN 1527525619 (electronic bk.)
Print version record.
Параллельные издания: Print version: : Marchand, Marie-Hélène. Story of the Pasteur Institute and its contributions to global health. - Newcastle upon Tyne, UK : Cambridge Scholars Publishing, 2018. - ISBN 9781527511736
Содержание:
Introduction -- Part I. The Pasteur Institute : a tale worth telling. A living landmark -- Pasteur's major contributions to the history of science and medicine -- Science at the Pasteur Institute -- Part II. Pasteur and his heirs. From one director to the next -- The virus of discord at the Pasteur Institute -- What it means to be a Pasteurian -- Emergence of the Pasteurian community around the world -- Part III. The continued influence of the Pasteur Institute. Worldwide recognition -- International friends of the Pasteur Institute -- Commemoration and celebration -- Stories about our bequests -- Conclusion.
~РУБ DDC 579.09
Рубрики: Academies and Institutes--history.
Microbiology--history.
Global Health--history.
Biomedical Research--history.
Microbiology--Research--History.--France
World health--History.
Microbiology--Research.
World health.
SCIENCE / Life Sciences / Biology
SCIENCE / Life Sciences / Microbiology
France.
France.
M 29
Marchand, Marie-Hélène,.
The story of the Pasteur Institute and its contributions to global health / / by Marie-Hélène Marchand. - Newcastle upon Tyne, UK : : Cambridge Scholars Publishing,, ©2018. - 1 online resource (xii, 190 pages) : : il, портр. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/2F3088C7-5A2C-4A8D-935C-2BE8634EF113. - ISBN 9781527525610 (electronic bk.). - ISBN 1527525619 (electronic bk.)
Print version record.
Параллельные издания: Print version: : Marchand, Marie-Hélène. Story of the Pasteur Institute and its contributions to global health. - Newcastle upon Tyne, UK : Cambridge Scholars Publishing, 2018. - ISBN 9781527511736
Содержание:
Introduction -- Part I. The Pasteur Institute : a tale worth telling. A living landmark -- Pasteur's major contributions to the history of science and medicine -- Science at the Pasteur Institute -- Part II. Pasteur and his heirs. From one director to the next -- The virus of discord at the Pasteur Institute -- What it means to be a Pasteurian -- Emergence of the Pasteurian community around the world -- Part III. The continued influence of the Pasteur Institute. Worldwide recognition -- International friends of the Pasteur Institute -- Commemoration and celebration -- Stories about our bequests -- Conclusion.
Рубрики: Academies and Institutes--history.
Microbiology--history.
Global Health--history.
Biomedical Research--history.
Microbiology--Research--History.--France
World health--History.
Microbiology--Research.
World health.
SCIENCE / Life Sciences / Biology
SCIENCE / Life Sciences / Microbiology
France.
France.
3.
Подробнее
S 31
Scheffler, Robin Wolfe,.
A contagious cause : : the American hunt for cancer viruses and the rise of molecular medicine / / Robin Wolfe Scheffler. - 7208/9780226628400. - Chicago : : The University of Chicago Press,, 2019. - 1 online resource (viii, 379 pages) : : il ( час. мин.), 7208/9780226628400. - In English. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/65358002-249A-4F96-A30B-7621C8387F21. - ISBN 9780226628400 (electronic bk.). - ISBN 022662840X (electronic bk.)
Print version record.
Параллельные издания: Print version: : Scheffler, Robin Wolfe. Contagious cause. - Chicago : The University of Chicago Press, 2019. - ISBN 9780226458892
Содержание:
Introduction: "an infectious disease, a virus" -- Cancer and contagion -- Cancer as a viral disease -- Policymakers and philanthropists define the cancer problem -- The biomedical settlement and the federalization of the cancer problem -- Managing the future at the special virus leukemia program -- Administrative objects and the infrastructure of cancer virus research -- Viruses as a central front in the war on cancer -- Molecular biology's resistance to the war on cancer -- The West Coast retrovirus rush and the discovery of oncogenes -- Momentum for molecular medicine -- Conclusion: afterlife, memory, and failure in biomedical research.
~РУБ DDC 616.99/4019
Рубрики: Oncogenic viruses--Research--History.--United States
Cancer--Etiology--Research--History.--United States
Virology--Research--History.--United States
Molecular biology--History.--United States
Oncogenic viruses.
Neoplasms--virology
Oncogenic Viruses
Virology--history
Molecular Biology--history
Biomedical Research--history
History, 20th Century
Virus oncogènes--Recherche--Histoire.--États-Unis
Cancer--Étiologie--Recherche--Histoire.--États-Unis
Virologie--Recherche--Histoire.--États-Unis
Biologie moléculaire--Histoire.--États-Unis
Virus oncogènes.
Médecine--Histoire, 20e siècle.
HEALTH & FITNESS--Diseases--General.
MEDICAL--Clinical Medicine.
MEDICAL--Diseases.
MEDICAL--Evidence-Based Medicine.
MEDICAL--Internal Medicine.
Cancer--Etiology--Research.
Molecular biology.
Oncogenic viruses--Research.
Virology--Research.
United States
United States.
Аннотация: Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer "germ," inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government's campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
S 31
Scheffler, Robin Wolfe,.
A contagious cause : : the American hunt for cancer viruses and the rise of molecular medicine / / Robin Wolfe Scheffler. - 7208/9780226628400. - Chicago : : The University of Chicago Press,, 2019. - 1 online resource (viii, 379 pages) : : il ( час. мин.), 7208/9780226628400. - In English. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/65358002-249A-4F96-A30B-7621C8387F21. - ISBN 9780226628400 (electronic bk.). - ISBN 022662840X (electronic bk.)
Print version record.
Параллельные издания: Print version: : Scheffler, Robin Wolfe. Contagious cause. - Chicago : The University of Chicago Press, 2019. - ISBN 9780226458892
Содержание:
Introduction: "an infectious disease, a virus" -- Cancer and contagion -- Cancer as a viral disease -- Policymakers and philanthropists define the cancer problem -- The biomedical settlement and the federalization of the cancer problem -- Managing the future at the special virus leukemia program -- Administrative objects and the infrastructure of cancer virus research -- Viruses as a central front in the war on cancer -- Molecular biology's resistance to the war on cancer -- The West Coast retrovirus rush and the discovery of oncogenes -- Momentum for molecular medicine -- Conclusion: afterlife, memory, and failure in biomedical research.
Рубрики: Oncogenic viruses--Research--History.--United States
Cancer--Etiology--Research--History.--United States
Virology--Research--History.--United States
Molecular biology--History.--United States
Oncogenic viruses.
Neoplasms--virology
Oncogenic Viruses
Virology--history
Molecular Biology--history
Biomedical Research--history
History, 20th Century
Virus oncogènes--Recherche--Histoire.--États-Unis
Cancer--Étiologie--Recherche--Histoire.--États-Unis
Virologie--Recherche--Histoire.--États-Unis
Biologie moléculaire--Histoire.--États-Unis
Virus oncogènes.
Médecine--Histoire, 20e siècle.
HEALTH & FITNESS--Diseases--General.
MEDICAL--Clinical Medicine.
MEDICAL--Diseases.
MEDICAL--Evidence-Based Medicine.
MEDICAL--Internal Medicine.
Cancer--Etiology--Research.
Molecular biology.
Oncogenic viruses--Research.
Virology--Research.
United States
United States.
Аннотация: Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer "germ," inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government's campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
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