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M 84
Morange, Michel,.
The black box of biology : : a history of the molecular revolution / / Michael Morange ; translated by Matthew Cobb. - Cambridge: : Harvard University Press ,, 2020. - 1 online resource (vi, 522 pages). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/BBFAE370-F24C-437E-A105-A018EC196590. - ISBN 0674245288 (electronic bk.). - ISBN 9780674245280 (electronic bk.)
Description based on online resource, title from digital title page (viewed on February 23, 2021).
Параллельные издания: Print version: : Morange, Michel Black box of biology. - Cambridge, Massachusetts : Harvard University Press, 2020. - ISBN 9780674281363
Содержание:
Part I. The birth of molecular biology: The roots of the new science -- The one gene-one enzyme hypothesis -- The chemical nature of the gene -- The phage group -- The birth of bacterial genetics -- The crystallization of the tobacco mosaic virus -- Enter the physicists -- The influence of the Rockefeller Foundation -- Physical techniques in molecular biology -- The role of physics -- Part II. The development of molecular biology: The discovery of the double helix -- Deciphering the genetic code -- The discovery of messenger RNA -- The French School -- Part III. The expansion of molecular biology: Normal science -- Genetic engineering -- Split genes and splicing -- The discovery of oncogenes -- From DNA polymerase to the amplification of DNA -- Part IV. Beyond molecular biology?: The molecularization of biology and medicine -- Protein structure -- The rise of developmental biology -- Molecular biology and evolution -- Gene therapy -- The central place of RNA -- Epigenetics -- Sequencing the human genome -- Systems biology and synthetic biology -- Images, representations and metaphors in molecular biology
~РУБ DDC 572.8
Рубрики: Molecular biology--History.
Molecular Biology--history.
SCIENCE / Life Sciences / Molecular Biology
Electronic books.
Molecular biology
Аннотация: "Over the past forty years a molecular vision has transformed biology. What began as an attempt to understand and explain life by looking at organisms at the microscopic level soon led to the rapid development of pathbreaking new technologies and discoveries that would change our understanding of science. In The Black Box of Biology Michel Morange shows that what led to this incredible transformation of biology was not an accumulation of new results, but the molecularization of a large part of biology. The expansion led to a cluster of explanatory tools and mechanisms used across biology and medicine. Yet, it was the fusion of the principles and concepts of molecular biology with those of other subdisciplines that led to the most decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs like the Human Genome sequencing program, and the emergence of new disciplines like synthetic biology, systems biology, and epigenetics. Yet the progress was not one sided. Morange reveals that molecular biology opened the black box of biology, and in turn, the discipline has been enriched by its expansion"--
Доп.точки доступа:
Cobb, Matthew, \translator.\
M 84
Morange, Michel,.
The black box of biology : : a history of the molecular revolution / / Michael Morange ; translated by Matthew Cobb. - Cambridge: : Harvard University Press ,, 2020. - 1 online resource (vi, 522 pages). - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/BBFAE370-F24C-437E-A105-A018EC196590. - ISBN 0674245288 (electronic bk.). - ISBN 9780674245280 (electronic bk.)
Description based on online resource, title from digital title page (viewed on February 23, 2021).
Параллельные издания: Print version: : Morange, Michel Black box of biology. - Cambridge, Massachusetts : Harvard University Press, 2020. - ISBN 9780674281363
Содержание:
Part I. The birth of molecular biology: The roots of the new science -- The one gene-one enzyme hypothesis -- The chemical nature of the gene -- The phage group -- The birth of bacterial genetics -- The crystallization of the tobacco mosaic virus -- Enter the physicists -- The influence of the Rockefeller Foundation -- Physical techniques in molecular biology -- The role of physics -- Part II. The development of molecular biology: The discovery of the double helix -- Deciphering the genetic code -- The discovery of messenger RNA -- The French School -- Part III. The expansion of molecular biology: Normal science -- Genetic engineering -- Split genes and splicing -- The discovery of oncogenes -- From DNA polymerase to the amplification of DNA -- Part IV. Beyond molecular biology?: The molecularization of biology and medicine -- Protein structure -- The rise of developmental biology -- Molecular biology and evolution -- Gene therapy -- The central place of RNA -- Epigenetics -- Sequencing the human genome -- Systems biology and synthetic biology -- Images, representations and metaphors in molecular biology
Рубрики: Molecular biology--History.
Molecular Biology--history.
SCIENCE / Life Sciences / Molecular Biology
Electronic books.
Molecular biology
Аннотация: "Over the past forty years a molecular vision has transformed biology. What began as an attempt to understand and explain life by looking at organisms at the microscopic level soon led to the rapid development of pathbreaking new technologies and discoveries that would change our understanding of science. In The Black Box of Biology Michel Morange shows that what led to this incredible transformation of biology was not an accumulation of new results, but the molecularization of a large part of biology. The expansion led to a cluster of explanatory tools and mechanisms used across biology and medicine. Yet, it was the fusion of the principles and concepts of molecular biology with those of other subdisciplines that led to the most decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs like the Human Genome sequencing program, and the emergence of new disciplines like synthetic biology, systems biology, and epigenetics. Yet the progress was not one sided. Morange reveals that molecular biology opened the black box of biology, and in turn, the discipline has been enriched by its expansion"--
Доп.точки доступа:
Cobb, Matthew, \translator.\
2.
Подробнее
S 31
Scheffler, Robin Wolfe,.
A contagious cause : : the American hunt for cancer viruses and the rise of molecular medicine / / Robin Wolfe Scheffler. - 7208/9780226628400. - Chicago : : The University of Chicago Press,, 2019. - 1 online resource (viii, 379 pages) : : il ( час. мин.), 7208/9780226628400. - In English. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/65358002-249A-4F96-A30B-7621C8387F21. - ISBN 9780226628400 (electronic bk.). - ISBN 022662840X (electronic bk.)
Print version record.
Параллельные издания: Print version: : Scheffler, Robin Wolfe. Contagious cause. - Chicago : The University of Chicago Press, 2019. - ISBN 9780226458892
Содержание:
Introduction: "an infectious disease, a virus" -- Cancer and contagion -- Cancer as a viral disease -- Policymakers and philanthropists define the cancer problem -- The biomedical settlement and the federalization of the cancer problem -- Managing the future at the special virus leukemia program -- Administrative objects and the infrastructure of cancer virus research -- Viruses as a central front in the war on cancer -- Molecular biology's resistance to the war on cancer -- The West Coast retrovirus rush and the discovery of oncogenes -- Momentum for molecular medicine -- Conclusion: afterlife, memory, and failure in biomedical research.
~РУБ DDC 616.99/4019
Рубрики: Oncogenic viruses--Research--History.--United States
Cancer--Etiology--Research--History.--United States
Virology--Research--History.--United States
Molecular biology--History.--United States
Oncogenic viruses.
Neoplasms--virology
Oncogenic Viruses
Virology--history
Molecular Biology--history
Biomedical Research--history
History, 20th Century
Virus oncogènes--Recherche--Histoire.--États-Unis
Cancer--Étiologie--Recherche--Histoire.--États-Unis
Virologie--Recherche--Histoire.--États-Unis
Biologie moléculaire--Histoire.--États-Unis
Virus oncogènes.
Médecine--Histoire, 20e siècle.
HEALTH & FITNESS--Diseases--General.
MEDICAL--Clinical Medicine.
MEDICAL--Diseases.
MEDICAL--Evidence-Based Medicine.
MEDICAL--Internal Medicine.
Cancer--Etiology--Research.
Molecular biology.
Oncogenic viruses--Research.
Virology--Research.
United States
United States.
Аннотация: Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer "germ," inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government's campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
S 31
Scheffler, Robin Wolfe,.
A contagious cause : : the American hunt for cancer viruses and the rise of molecular medicine / / Robin Wolfe Scheffler. - 7208/9780226628400. - Chicago : : The University of Chicago Press,, 2019. - 1 online resource (viii, 379 pages) : : il ( час. мин.), 7208/9780226628400. - In English. - Includes bibliographical references and index. - URL: https://library.dvfu.ru/lib/document/SK_ELIB/65358002-249A-4F96-A30B-7621C8387F21. - ISBN 9780226628400 (electronic bk.). - ISBN 022662840X (electronic bk.)
Print version record.
Параллельные издания: Print version: : Scheffler, Robin Wolfe. Contagious cause. - Chicago : The University of Chicago Press, 2019. - ISBN 9780226458892
Содержание:
Introduction: "an infectious disease, a virus" -- Cancer and contagion -- Cancer as a viral disease -- Policymakers and philanthropists define the cancer problem -- The biomedical settlement and the federalization of the cancer problem -- Managing the future at the special virus leukemia program -- Administrative objects and the infrastructure of cancer virus research -- Viruses as a central front in the war on cancer -- Molecular biology's resistance to the war on cancer -- The West Coast retrovirus rush and the discovery of oncogenes -- Momentum for molecular medicine -- Conclusion: afterlife, memory, and failure in biomedical research.
Рубрики: Oncogenic viruses--Research--History.--United States
Cancer--Etiology--Research--History.--United States
Virology--Research--History.--United States
Molecular biology--History.--United States
Oncogenic viruses.
Neoplasms--virology
Oncogenic Viruses
Virology--history
Molecular Biology--history
Biomedical Research--history
History, 20th Century
Virus oncogènes--Recherche--Histoire.--États-Unis
Cancer--Étiologie--Recherche--Histoire.--États-Unis
Virologie--Recherche--Histoire.--États-Unis
Biologie moléculaire--Histoire.--États-Unis
Virus oncogènes.
Médecine--Histoire, 20e siècle.
HEALTH & FITNESS--Diseases--General.
MEDICAL--Clinical Medicine.
MEDICAL--Diseases.
MEDICAL--Evidence-Based Medicine.
MEDICAL--Internal Medicine.
Cancer--Etiology--Research.
Molecular biology.
Oncogenic viruses--Research.
Virology--Research.
United States
United States.
Аннотация: Is cancer a contagious disease? In the late nineteenth century this idea, and attending efforts to identify a cancer "germ," inspired fear and ignited controversy. Yet speculation that cancer might be contagious also contained a kernel of hope that the strategies used against infectious diseases, especially vaccination, might be able to subdue this dread disease. Today, nearly one in six cancers are thought to have an infectious cause, but the path to that understanding was twisting and turbulent. A Contagious Cause is the first book to trace the century-long hunt for a human cancer virus in America, an effort whose scale exceeded that of the Human Genome Project. The government's campaign merged the worlds of molecular biology, public health, and military planning in the name of translating laboratory discoveries into useful medical therapies. However, its expansion into biomedical research sparked fierce conflict. Many biologists dismissed the suggestion that research should be planned and the idea of curing cancer by a vaccine or any other means as unrealistic, if not dangerous. Although the American hunt was ultimately fruitless, this effort nonetheless profoundly shaped our understanding of life at its most fundamental levels. A Contagious Cause links laboratory and legislature as has rarely been done before, creating a new chapter in the histories of science and American politics.
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